NPP Genetix Pharma or nandrolone phenpropionate sold under the brand name Durabolin among others is an androgen and anabolic steroid Nandrolone phenylpropionate, also known as nandrolone phenylpropionate, is a synthetic androgen and anabolic steroid and a nandrolone ester. Nandrolone phenylpropionate, when administered via intramuscular injection, has an active life of approximately 3 to 5 days. Durabolin is almost always sold in its esterified form, either as nandrolone phenylpropionate or as nandrolone decanoate.
NPP Genetix Pharma is used for physique- and performance-enhancing purposes by competitive athletes, bodybuilders, and powerlifters. It is a popular steroid for strength and size gains, particularly among users interested in increasing muscle mass and performance without adding much body fat. As it is anabolic, it can also be used to increase muscle mass and performance in hypogonadal men (e.g. in the treatment of HIV AIDS). Nandrolone phenylpropionate is generally stacked with other anabolic agents, such as testosterone, methenolone, or oxandrolone. Nandrolone is also sometimes stacked with non-steroidal agents such as trenbolone or stanozolol.
NPP Genetix Pharma is available in injectable form. the injectable is sold as Deca-Durabolin, Durabolin S, and many others. Nandrolone is an androgen and anabolic steroid or an agonist of the androgen receptor (AR). It is structurally related to dihydrotestosterone (DHT), with two of the four methyl groups on the DHT molecule replaced with a phenyl group. As a result of this alteration, nandrolone has diminished androgenic potency relative to DHT. Relative to testosterone (T), nandrolone has a somewhat reduced affinity for androgen receptors but nonetheless has strong androgenic activity. The potency of nandrolone and its derivatives as anabolic agents is considered to be at least equal to that of testosterone and greater than that of DHT.
Like other AAS, nandrolone has been reported to augment levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the body. It is inhibitory of testosterone production in the testes, thus reducing levels of this hormone in plasma. This effect may be especially pronounced when the drug is administered along with testosterone, a combination that causes a reduction of testosterone production of up to 70%. Nandrolone may inhibit the enzyme aromatase, which converts androgens into estrogens (via estradiol). As a result, nandrolone may decrease estrogen levels in the body. Nandrolone has also been shown to suppress levels of corticosteroid-binding globulin (CBG), a protein that reduces the activity of glucocorticoids in the body. The pharmacokinetics of nandrolone have been investigated. Nandrolone is metabolized by the body into various inactive metabolites. The elimination half-life of nandrolone is reported to be approximately 6 hours under normal conditions, with about 95% of a dose being excreted within 72 hours of administration.
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