Zionova Accutane 20mg
Isotretinoin · 20 mg
$2.40 per tablet
Zionova Accutane 20mg: Isotretinoin, 20 mg per tablet, 50 tablets. Ships from inside Canada in plain packaging, with tracking within 72 hours; free Canada Post shipping over $300.
Complete your cycle
What most customers add with this:
- Compound
- Isotretinoin
- Strength
- 20 mg per tablet
- Pack
- 50 tablets
- Total per order
- 1,000 mg
- Half-life
- About 20 hours
- Form
- Tablets
About Zionova Accutane 20mg
Isotretinoin (Accutane) is a vitamin-A-derived medicine for severe acne that has not responded to other treatment. It is powerful and closely regulated because of birth-defect risk.
Zionova: Each order is 50 tablets, 20 mg each (1,000 mg in total).
Commonly used for
- Severe, scarring acne
- Acne worsened by steroid use
Compound profile
- Formula
- C20H28O2
- Molecular weight
- 300.4 g/mol
- CAS number
- 4759-48-2
- PubChem
- CID 5282379
How it works
It shrinks the skin’s oil glands and cuts oil production, which removes the conditions acne bacteria need.
Half-life: about 20 hours.
Release profile
How levels rise and fall after a single dose, based on a half-life of about 20 hours. Each mark on the axis is one half-life; after about five, almost none is left.
An illustration from the half-life only; real levels vary with dose, food, how quickly it is absorbed and the person.
Clinical reference dose
Clinical reference: the label dose is 0.5–1 mg per kg of body weight a day, split into two doses with food, for about 15–20 weeks. Lower doses are often used for milder cases.
Tablets here are 20 mg each.
In Canada it is prescribed under a pregnancy-prevention program with monthly checks.
These are reference amounts from labels and clinical studies, not a personal recommendation. A doctor sets the right dose for you, using your bloodwork.
Measuring calculator
Enter the amount you have been prescribed or are working from, and this works out exactly what to measure from this product. It doesn’t suggest an amount.
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Arithmetic only, from the strength on this product’s label. Check the label on your vial or bottle, follow your prescriber, and ask a pharmacist if you’re unsure how to measure.
Combinations and interactions
Often compared or used with
- Not combined with tetracycline antibiotics (raised pressure in the skull).
- Oral steroids and isotretinoin both stress the liver and lipids; doctors avoid using them together.
Interactions to know
- Vitamin A supplements: toxicity.
- Tetracyclines (doxycycline, minocycline): raised intracranial pressure.
- Alcohol: extra liver and lipid strain.
Tell your doctor and pharmacist about everything you take, including supplements, before adding anything new.
Side effects and risks
Birth defects
Severe birth defects; must never be used in pregnancy.
Mood
Depression and mood changes have been reported; stop and get help if mood drops.
Dryness
Very dry lips, skin and eyes.
Liver and lipids
Raised triglycerides and liver enzymes.
Are pregnant or could become pregnant, are breastfeeding, have liver disease, very high triglycerides or a history of depression.
In Canada: Isotretinoin is a prescription drug in Canada. Talk to a doctor or pharmacist about whether it is right for you.
Common questions
What bloodwork is needed?
Liver enzymes and fasting lipids before starting and during treatment.
How fast does it ship?
Orders ship from inside Canada with a tracking number within 72 hours of payment. Weekend orders are packed on Sunday or Monday. Canada Post Xpresspost takes 2–5 business days to most cities; UPS or FedEx is faster. Shipping is free by Canada Post over $300 and by UPS or FedEx over $1,000.
How is it packaged?
In a plain box with no product names or branding on the outside.
Is isotretinoin legal in Canada?
Isotretinoin is a prescription drug in Canada. Talk to a doctor or pharmacist about whether it is right for you.
Sources
- Management of Acne Vulgaris: A ReviewEichenfield DZ et al. · JAMA · 2021 · PMID 34812859
- Isotretinoin for acne vulgaris – an update on adverse effects and laboratory monitoringFallah H, Rademaker M · J Dermatolog Treat · 2022 · PMID 34379039
Chemical data and structures: PubChem, U.S. National Library of Medicine. Protein sequences: UniProt.
Specifications
| Compound | Isotretinoin |
|---|---|
| Strength | 20 mg per tablet |
| Pack | 50 tablets |
| Total per order | 1,000 mg |
| Half-life | About 20 hours |
| Form | Tablets |
| Brand | Zionova |
| SKU | ZIO-ACCUTANE-20MG |
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This information is educational and is not medical advice. Talk to a doctor or pharmacist before using any hormone, peptide or prescription drug. For adults 18+ only.